The Serrano San Francisco is within short distance of Union Square, Coit Tower, the Theater District, the Moscone Convention Center, and more. Visitors will be can stay other regions of the town easily as well, including the Financial District, Fisherman's Wharf, Chinatown, and more. Clients at the Hotel Serrano San Francisco are within a short ride of the San Francisco International Airport and the Oakland airport. Many sights are within short distance, and guests will be can take the cable autos, taxis, and buses to other regions of the town.

A few of the facilities found in the 236 suites at the Serrano San Francisco Ca comprise flat screen televisions, high-speed Internet access, bathrobes, Moroccan décor, and cherry forest furniture and accessories.

Guests staying at the Serrano Hotel San Francisco will find that the 17-story Spanish Revival hotel provides valet car park, clothes laundering service, and wine receptions in the evening, in addition to a sport centre, steam apartment, and massage apartment. The hotel can propose an onsite restaurant called Ponzu and additionaly savoury coffee and tea in the morning.