Situated in the Nob Hill region of the town, the Mark Hopkins SF is only a short meander from Chinatown, the Financial District, and Union Square. Visitors at the guesthouse will also be can stay some of the more prominent sites in the town, including Fisherman's Wharf and the Golden Gate Bridge. The InterContinental Mark Hopkins San Francisco is within a short distance of park amusements, in addition to the crossing location of 3 cable auto lines. Further to, the guesthouse is only 17 miles from the San Francisco International Airport and 22 miles from Oakland International Airport.

The apartments situated in the InterContinental Mark Hopkins comprise in suite safes, mini bars, coffeemakers, and much more.

Opened in 1926, the InterContinental Mark Hopkins Hotel stresses a tennis court, sport heart, 24-hr apartment amenities, washhouse and dry cleaning, shoeshine facilities, valet parking zone for a fee, a gift boutique and newsstand, and more. Customers will also find Nob Hill Restaurant, where they able to grab a bite to eat. The Top of the Mark brasserie is on the nineteenth floor.